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Evidence is increasing that every addiction without exception is related to problems with the brain's reward center, especially the mesolimbic system. This area of the problem regulates reward responses in establishing food and sex, plus in nurturing infants and children. One of the most important neurotransmitters involved with reward responses, both once they malfunction and when they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the amount of dopamine released in in response to a stimulus"(Bostwick & Bucci, 2008).

Using two separate drugs to shed weight can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you should err assisting caution and allow FDA do its job and demand some investigation be done so the public understands the side effects and risks of the medications before we drive them. Keep in mind that drug companies are in business to generate money and that they would say almost anything to keep people on the medications.

Researchers discovered that participants investing in this drug for any year, lost weight within 4 weeks and have kept the load off throughout the 56 weeks in the study. Contrave can be a combination in the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs which are made up of many active ingredient, which might make them more potent and safer.

Combo-pilling will be the newest fad or also the newest ahead under scrutiny and for that reason it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular will be the fact that since right now there aren't any long term prescription diet pills that have been licensed by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be licensed by the FDA.

Seizures really are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug may also raise hypertension and heartrate, and must not be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure and heartbeat and must stop used in patients with uncontrolled high blood pressure levels, along with by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients which has a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients to the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking.

--Participating in support groups that really help the family of the addict recover (for example Al-Anon or Nar-Anon).